TDA™ Technology—Targeted
Dermal Application
by Dermadrop

TDA™ — next-generation non-invasive skin therapy. Globally patented innovation backed by EU Horizon 2020 funding and clinically validated research.

Experience the next generation of non-invasive skin therapy. TDA™ — a globally patented innovation, powered by EU Horizon 2020, Swiss & German federal innovation funding, and backed by peer-reviewed research. Internationally recognized, clinically validated, and scientifically proven.

Partner with
DERMADROP TDA™

MEDICAL-GRADE OXYGEN+ MICROUNIT SYSTEM

  • Dermadrop TDA™ begins by extracting ambient air and converting it into medical-grade oxygen through advanced filtration. Within the patented Handpiece, this oxygen merges with active substances to form high-velocity micro-units.

  • Propelled at supersonic speeds and under controlled pressure, these units deliver active ingredients with precision — ensuring contactless delivery of active substances without pain, mechanical stress, tissue disruption, or any damage to the skin.

LP3-COMPLEX – LIPOSOMAL CARRIER FOR DEEP DELIVERY

  • Each treatment substance is powered by our clinically proven LP3-Complex — a cutting-edge liposomal carrier designed to enhance the skin’s permeability up to 65% by opening the lamellar structure of the epidermis.

  • This smart delivery system helps active ingredients bypass the epidermal barrier and reach deep into the dermal layers, precisely where they’re needed most.

DERMAL DEPOT TECHNOLOGY FOR LONG-LASTING RESULTS

  • Once delivered into the skin, the active substances form stable dermal depots that continue to release their benefits over time. With each session, these reservoirs build up and enhance the skin’s natural regenerative capacity.

Scientific Proof &
Research Scientific Validation
& Published Research

TDA™ Technology has been proven effective in independent studies for transdermal delivery and dermal deposition.

A scientifically validated system, TDA™, enhances topical delivery performance in both human and veterinary dermatology.

  • Pharmaceutics (2022)

    Effect of an Oxygen-Based Mechanical Drug Delivery System — a Franz-cell study using porcine skin demonstrated that oxygen-powered delivery using the TDA™ system significantly enhanced the penetration of actives such as diclofenac, indomethacin, and salicylic acid compared to passive pipette application.

    Go to the article

  • BMC Veterinary Research (2024)

    Potent drug delivery enhancement of Betulinic Acid and NVX-207 — validated both in vitro and in vivo, this study demonstrated improved skin penetration and depot formation when using oxygen-flow assisted (OFA) delivery through the TDA™ device.

    Go to the article

  • University of Zurich & Vetsuisse Faculty (2023)

    OFA-assisted delivery of methotrexate showed significantly deeper dermal distribution and faster clinical improvement in horses with equine melanoma. Method used: TDA™ system with lipid-based carriers. The work builds on earlier veterinary studies to establish repeatable results.

    Go to the article

Inside Meddrop BMT: Visionaries of Non-Invasive Delivery

Meddrop BioMedical Technologies GmbH
is a German medical engineering company behind the invention and development of TDA™ Technology. Established in Hamburg, the company focuses on pioneering non-invasive delivery systems that merge dermatology, biotechnology, and oxygen physics.

  • Headquarters: Hamburg, Germany
  • Focus: Medical-grade transdermal systems, liposomal transport science, oxygen-based propulsion
  • Scientific Partnerships: Collaborations with Vetsuisse Faculty (University of Zurich), Charité Berlin, University of Göttingen, and TÜV Rheinland
  • Awarded multiple patents across the EU, USA, and Asia

Its solutions are actively used in clinics across more than 28 countries worldwide.

Go to official website

International Grants
&
Recognition

Non-invasive procedures are essential in modern aesthetics, as they are the fastest-growing and most in-demand segment of cosmetic medicine.

These strategic grants confirm the value of TDA™ as a research-worthy and innovation-certified platform at the intersection of medical engineering, dermatology, and pharmaceutical delivery.

What TDA™ does —
Measurable Results What TDA™ Really Does
— with Measurable Results

Non-invasive aesthetics have become essential, with minimally invasive technologies leading as the fastest-growing segment in cosmetic medicine.

Enhanced Penetration with LP3-Complex™

Visual comparison: skin before and after LP3-enhanced TDA™ showing the difference in penetration depth and skin density.

LP3-Complex™ has been shown to improve skin permeability by increasing the thickness of the upper skin layer (epidermis) by 65%, as measured by high-frequency ultrasound.

Partner with
Dermadrop TDA™

What do we offer:

    • German-engineered technology with proven profitability and fast ROI
    • 100% needle-free treatments your clients actually ask for
    • High demand: Over 61% of adults avoid needles (IJD, 2023)
    • Predictable cost per session, scalable for any clinic size
    • Now in the UAE — be among the first to offer this innovation